The BRCA genes are well-known for their association with breast cancer and ovarian cancer, but they also play a significant role in other types of cancer, including pancreatic cancer (PDAC). The lifetime risk of developing pancreatic cancer is about 1.8% for men and 1.7% for women, but for those with BRCA mutations, the risk increases to 5-10%.
Annual Report to the Nation: Cancer Deaths Continue Downward Trend; Modest Improvements in Survival for Pancreatic Cancer
Overall cancer death rates continued to decline among men, women, children, and adolescents and young adults in every major racial and ethnic group in the United States from 2015 to 2019, according to the latest Annual Report to the Nation on the Status of Cancer. From 2014 to 2018, overall cancer incidence, or new cases of cancer, remained stable for men and children but increased for women and adolescents and young adults. This year’s report, published October 27, 2022, in Cancer, also highlights longer-term trends in pancreatic cancer, as well as racial and ethnic disparities in incidence and death rates for many individual cancer sites.